“The lobule‐density divergence is best explained by cell‐segmentation artifacts rather than true biology. One pipeline’s reliance on aggressive nuclear‐expansion segmentation likely causes smaller lobules to fuse with adjacent ducts (segmentation bleed), producing an apparent density drop, whereas another using stricter cytoplasmic‐boundary detection preserves lobule counts, showing no change. By standardizing segmentation methods and reporting boundary‐detection parameters, these conflicting trends can be reconciled and reproducible measures of breast tissue aging ensured.”