
A new integrated program aims to standardize epigenetic assays and extend research on epigenetic therapies in immuno‐oncology, promising significant advancements in both medical and environmental fields. This initiative leverages insights from DNA methylation and histone modifications to boost precision medicine and enhance biodiversity monitoring, while addressing public concerns regarding mood-related applications. With a focus on validating findings within complex ecosystems, the program seeks to manage expectations around epigenetic outcomes in both health and environmental resilience.
“The Institute was recently awarded a grant from The Leona M. and Harry B. Helmsley Charitable Trust for a project Dr. Laird will lead to investigate possible links between Crohn’s and epigenetics.”
“As scientists uncover and better understand the epigenetic markers associated with ADHD, the hope is that this information will contribute to the development of new precision medicine toolkits for better detection, monitoring, and treatment formulation.”
“While we’ve attempted to specify presentations of ADHD — predominantly inattentive, predominantly hyperactive/impulsive, and combined presentation — we are simply not yet good at separating and understanding why individuals with ADHD follow such different courses and clinical presentations.”
“Histone modifications act in the regulation of gene transcription, as they interfere with chromatin condensation, which is directly related to whether DNA regions are accessible or inaccessible to the transcriptional machinery.”