Amgen Inc. delivered an impressive fourth quarter for 2025, reporting revenues of $9.87 billion—an 8.6% year-on-year increase that surpassed Wall Street estimates. This strong performance, driven by robust sales of key products, triggered an over 8% rise in share price, renewing investor confidence. Despite challenges from biosimilars and anticipated sales erosion of some established drugs, Amgen's optimistic 2026 guidance of $37 billion to $38.4 billion in revenue and ongoing development in new therapies position the firm favorably in the competitive landscape.

“Amgen exceeded fourth-quarter expectations on strong sales of its biggest medicines, and forecast 2026 performance that aligns with what Wall Street is anticipating.”
“Thankfully, over the next few years, Amgen should earn approval for several newer products. The company's bemarituzumab, an investigational therapy for gastric cancer, performed well in phase 3 studies last year, as did rocatinlimab, a medicine for eczema.”
“For you, the key takeaway is that management is willing to walk from a late-stage atopic dermatitis drug while still defending an approved rare-disease therapy, which may signal where it sees the strongest risk adjusted returns across a crowded field that includes Sanofi, Regeneron and AbbVie.”